The effects of drugs and other agencies upon the respiratory movements / by Horatio C. Wood ; assisted by David Cerna.

  • Wood, Horatio Curtis, 1841-1920.
Date:
1892
Catalogue details

Licence: Public Domain Mark

Credit: The effects of drugs and other agencies upon the respiratory movements / by Horatio C. Wood ; assisted by David Cerna. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    These experiments show that both in the normal and in the chloralized dog, the salts of atropine greatly increase the respiratory movement of air, and lead to the conclusion that atropine is a direct and powerful stimulant to the respiratory function. The experiments which we have made with strychnine upon the normal animal are as follows: Experiment XXXI. Time min. Strychnine grammes Aii- movement cubic ft. Resp. rate Remarks 0 0-05 95 Weight 9 kilos. 3 0-0002 • 12 0-0004 19 0-11 74 Dog quiet,buthas spasms when touched. 27 0-06 42 0-0004 50 0-06 30 Pronounced spasms. 56 0-11 33 Dog very quiet. Experiment XXXII. 0 0-14 54 Weight 9-9 kilos. 10 0-0005 20 0-31 Died three minutes later. Experiment XXXIII. 0 0-1 Weight 9-9 kilos. 5-15 0-0007 25 0-46 Dog quiet. 33 0-21 Experiment XXXIV. 0 0-09 30 Weight 8 kilo 2 0-0005 14 0-1 25 23 0-09 24 26 0-0005 33 0-14 28 Reflexes abnormally active. 42 0-12 24 46 0-0005 51 0-154 27 Slight spasms. 60 0-36 94 Dog quiet. 70 0-262 88