The integration of the endocrine system : being the fifth Horsley memorial lecture, delivered at the University College Hospital Medical School / by Sir Walter Langdon-Brown.

  • Langdon-Brown, W. (Walter), 1870-1946.
Date:
1935
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Licence: In copyright

Credit: The integration of the endocrine system : being the fifth Horsley memorial lecture, delivered at the University College Hospital Medical School / by Sir Walter Langdon-Brown. Source: Wellcome Collection.

    19/70 (page 11)
    In these instances we are dealing with partial lesions which no doubt have an irritative effect on the remainder. But I will now refer to an extra¬ ordinary case under the care of Professor Naish1 of Sheffield, in which a teratoma involving the whole of the hypothalamus completely blotted out the normal expression of the emotions; in Hughlings Jackson’s nomenclature, a destroying rather than a discharging lesion. A girl aged io came under observation with the following history. From birth she had been of an unusual temperament; the contrast being made more manifest to her parents after the birth of the second child who had normal reactions. As an infant she used to sleep considerably longer hours than the average for her age, and during her sleep she would never move. As she grew older it was noticed that she was very undemonstrative in the expression of emotions; she never showed joy or excitement. She never showed fear in the usual way, although she apparently felt fear, especially of loud noises, darkness, solitude, and certain persons. She would tell her parents that she was afraid, but her expression and voice were calm. («)