Clinical genetics / edited by Arnold Sorsby.

Date:
1953
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Clinical genetics / edited by Arnold Sorsby. Source: Wellcome Collection.

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    (с) id) Plate 1 Generalized dominant fundus dystrophy. Range of ophthalmoscopic appearances as seen in one family. (After A. Sorsby and M. E. JoU Mason {1949). Brit. J. Ophthal., 33, 67.) (a) Earliest stage showing neuro-retinal oedema, haemorrhages and exudates in a patient aged 41 years. (b) The same eye 22 months later, showing scar formation, (c) Appearances in a cousin of the patient at the age of 68 years; patterned exudates, pigmentary reaction, and early choroidal sclerosis are all evident, (d) Appearances in an uncle at the age of 57 years. There is con¬ siderable atrophy, (e) Appearances in an aunt at the age of 77 years. There is extensive atrophy and considerable choroidal sclerosis, and some pigmentary disturbance. There is also a coin¬ cidental glaucomatous optic atrophy. These illustrations show that lesions generally ascribed to environmental factors occur in a clearly genetic affection. [7b face p. 2