Clinical genetics / edited by Arnold Sorsby.

Date:
1953
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Clinical genetics / edited by Arnold Sorsby. Source: Wellcome Collection.

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    CLINICAL VARIETIES OF GENETIC DISEASE anomalies. These considerations emphasize the tenuous nature of any attempt to sort out different varieties of genetic disease as fundamentally different entities. Until a clearer understanding of the mechanism of the gene is obtained, the clinical groupings employed currently serve a useful purpose in classification and description. SCHEMATIC PRESENTATION In general terms it may be said that there is strong presumptive evidence that some pathological processes are largely genetically determined, whilst in others disease is largely a matter of the interaction of genetic and environmental factors with variable stress on one or the other. Relatively few affections are entirely environmental in origin. Schematically this is represented in the following Table. TABLE Schematic Representation of the Significance of Hereditary Influences in Pathological Disturbances 8