Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine, cinchonine ... / with an introduction and copious notes, by the late Charles Thomas Haden ; translated from the 'Formulaire ... par F. Magendie. Troisième édition, 1822.'.

  • Magendie, François, 1783-1855.
Date:
1823
Catalogue details

Licence: Public Domain Mark

Credit: Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine, cinchonine ... / with an introduction and copious notes, by the late Charles Thomas Haden ; translated from the 'Formulaire ... par F. Magendie. Troisième édition, 1822.'. Source: Wellcome Collection.

    43/134 (page 21)
    of procaring this base in a state of purity. He precipitates a strong infusion of opium by caustic ammonia. He separates the brownish white precipitate by means of the filter. He evaporates the infusion to a sixth of its volume ; and on mixing it with a fresh quantity of am¬ monia, he obtains a new precipitate of pure morphine. He gives time for the deposit to form ; he then separates it, by means of the filter, and washes it with cold water. After it is sufficiently drained, he sprinkles it with a little alcohol, which he permits to pass through the filter ; this fluid dissolves a large portion of the colouring matter, and also a little of the morphine. He then entirely dissolves the morphine in acetic acid, and takes away the colouring matter which remains, by treating the solution with a little ivory-black. He shakes this mixture often during twenty-four hours, and then throws it on the filter. The li¬ quid passes through entirely colourless ; and on treating it again by ammonia, the morphine is precipitated in the form of a white powder. If this base be thèn dissolved in alcohol, and the solution be permitted to evaporate spon¬ taneously, the morphine crystallizes in the form of beautiful regular crystals. These crystals are perfectly white, have a slight opaline trans-