The anatomy and development of rodent ulcer : a Boylston Medical Prize essay for 1872 / by J. Collins Warren.

  • Warren, John Collins, 1842-1927.
Date:
1872
Catalogue details

Licence: Public Domain Mark

Credit: The anatomy and development of rodent ulcer : a Boylston Medical Prize essay for 1872 / by J. Collins Warren. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    ing with other similar masses, and presenting fre- quent constrictions. (See Drawing G.) At other points, generally near the periphery of the growth, the form was oval. The most marked peculiarity of the cells was their small size, con- trasting greatly with the large pavement epithe- lium cell that is found in cancer of the lower lip. They contained an oval, well defined granular nucleus, which colored readily with carmine, at those points where the structure was not beginning to break down. When the cells were not closely crowded together, their form was either globular, or the borders of the cells were not well defined, the nuclei appearing imbedded in a continuous mass of protoplasm. At certain parts of the edges of these cell structures, the cells resembled cylinder epithelium, reminding one of the shape and ar- rangement of the epithelium immediately sur- rounding the papillae of the skin. Nearly all of the cell-nests contained the epidermic balls, in the immediate neighborhood of which the cells were, of course, more or less flattened out. (Drawing 6.) These balls, however, are by no means as large, nor did they catch the eye as easily as those very striking forms which predominate to such an ex- tent in the large cell epithelial cancers, like cancer of the lip. It may be said of the cells in general,