The anatomy and development of rodent ulcer : a Boylston Medical Prize essay for 1872 / by J. Collins Warren.

  • Warren, John Collins, 1842-1927.
Date:
1872
Catalogue details

Licence: Public Domain Mark

Credit: The anatomy and development of rodent ulcer : a Boylston Medical Prize essay for 1872 / by J. Collins Warren. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    which the cells lie, appear to be spaces intervening between the connective tissue fibres, and the walls of a vessel. We have seen, in Drawing 4, the ves- sel penetrating the young cell-clusters. As these latter mature, the circulation is probably cut oft* by the increased pressure around the vessel, and its walls finally disappear, or are seen as a bundle of fibres, penetrating the alveolus for a short distance. (Drawing 3.) This disposition of the cell-clusters is obviously different from what we find in the last three cases. In these, the cells are contained in an anastomosing system of tubes, and form quite an ornamental net- work occupying the full thickness of the skin. The disposition of the spaces reminds one strongly of the now well-known system of plas- matic canals, from which the lymphatic capillaries take their origin. Indeed it is quite possible that the lymphatics, themselves, may have been invaded for a certain distance, though this Avas a point which could not be demonstrated. There was no epithelial lining to the tubes to be seen, indicating their lymphatic nature. (See Ivoester. Entwicke- lung der Careinome.) In all cases, then, we find the cells forming in spaces in the connective tissue of the cutis. In one set of cases these spaces surround the vessels of 5