On the functional diseases of the renal, urinary, and reproductive organs : with a general review of urinary pathology / by D. Campbell Black.

  • Black, D. Campbell (Donald Campbell), 1841-1898.
Date:
1872
Catalogue details

Licence: Public Domain Mark

Credit: On the functional diseases of the renal, urinary, and reproductive organs : with a general review of urinary pathology / by D. Campbell Black. Source: Wellcome Collection.

    67/396 (page 39)
    error, it is impossible to come to any other conclusion than that excessive and prolonged muscular exertion increases enormously the excretion of nitrogen, and that the excess of nitrogen discharged is due to an increased disassimilation of the muscular substance ; and it is to be remembered that the experiments on which this statement is based were made with a diet regulated solely by the taste of the individual. This question, then, may at least be said to be suh judice. How does it alfect the pathology and therapeutics of gout and rheumatism? It is admitted that urea, carbonic acid, water, and ammonia, &c., are the results of the ultimate oxidation of effete tissue; but it does not follow that these are the results of direct oxidation; nay, it is rather more probable that they are the results of a series of chemical evolutions. If they are the results of oxidation, and if in certain states, as under the influence of great bodily exertion, a relatively larger amount of oxygen is consumed by the body, the con- clusion is irresistible that increased tissue metamor- phosis must be manifested in increased excretion, if not in urea, at least in some of the other excretions, such as carbonic acid and water. According to Dr Smith, carbonic acid is much increased by muscular exertion. It is not absolutely contended, then, that urea is directly formed in the depths of the tissues, as the researches of Dr Parkes and others render it highly probable that the liver is the organ by which urea is elaborated from less oxidised material presented to it.^'' * In the Centralblatt fiir Medizin Wissenschaft, Dr Cyon, of St Peters- burg, has published the result of researches made by him on this subject. Blood withdrawn from the carotid arteries of dogs was rapidly defibrinated; a portion of it was pUiCed in an apparatus by which it was propelled by me-