Collection of iatrochemical receipts and notes on medicine in Latin and English. The first part, possibly by Ruthven himself, is followed by 'Experimenta' of Sir Robert Killigrew. With other receipts. Some headings and many marginal notes in red. Contents: (1) De mercurio vitae varia ex relatione D. Ruthuen. (ff. 2, 3) (2) Iatrochemical receipts and notes on medicine, perhaps written by Ruthven himself. (ff. 22-88) (3) Sequentia ex variis confabulationibus habitis cum D. Ruthueno. (ff. 88v-94) (4) Medical receipts in English by a different hand. (ff. 101-115) (5) Experimenta Equitis D. Roberti Killigrew, ab ipso probata. (ff. 117-122) (6) Great Cordiall. Sir Robert Killegrew. 1630. (fol. 123) (7) Medical receipts in English: by the same hand as No. 4 (ff. 124, 125) Nos. 1,3, and perhaps 6, together with the marginal annotations to No. 2 are by the same hand, whose initials 'RVT' are given in a monogram on ff. 46, 47v, 48, 54 and 69v. An inscription on the spine is: 'RVT Cl[assis] g'. The date 1613 occurs on fol. 64.