Segment 1 Gilliland introduces Dollery, Conolly and Davies. A film is shown of a dispensary department in a hospital, including shots of medicines on shelves and a close-up of a prescription. Dollery gives statistics for how many drugs a hospital patient is likely to receive and cautions against the prescribing of drugs which, in combination, might interact negatively. Dollery speaks to the camera and shows a diagram detailing the main sites in the body where drug interactions might occur. He then describes the physiological processes by which drugs are absorbed within the whole body. He introduces Conolly to discuss drug interactions that occur at the site of action. Time start: 00:00:00:00 Time end: 00:08:02:00 Length: 00:08:02:00
Segment 2 Conolly discusses various ways in which drugs interact with each other. He shows a diagram of a specific drug, Allopurinol, and describes the effect this particular drug has on other drugs. He discusses Insulin in some depth as Insulin is both a crucial drug for diabetics, but also a difficult drug to combine with other medications. Conolly shows diagrams relating to the interactions of some anti-depressant medications with some drugs used for the treatment of hypertension; he uses charts and diagrams to illustrate his points. Time start: 00:08:02:00 Time end: 00:16:06:20 Length: 00:08:04:20
Segment 3 Davies talks to camera. He describes how drugs cause different reactions at different receptor sites in the body. Using charts and diagrams he shows, in detail, how these reactions manifest themselves. Time start: 00:16:06:20 Time end: 00:21:24:20 Length: 00:05:18:00
Segment 4 Davies talks to camera. He describes some real case studies in which different drug combinations have had an effect on each other. He uses graphs to show how these interactions occur. He focuses in particular on the role of the liver in metabolising various medications. Time start: 00:21:24:20 Time end: 00:24:14:00 Length: 00:02:49:05
Segment 5 Dollery, Conolly and Davies are shown seated in discussion. Dollery begins and asks Conolly to provide guidance for doctors about particular situations in which drug interactions might occur. Conolly describes which drugs should be looked out for as potentially vulnerable to interactions. Dollery asks Davies to talk about the sort of non-prescribed medications that might have bad interactions with prescribed drugs. Davies gives examples of different substances that might interact badly with prescription drugs. He and Dollery discuss this in relation to many different types of drugs. Finally, Dollery sums up the main points of the lecture. Time start: 00:24:14:00 Time end: 00:30:05:16 Length: 00:05:51:16