Fever : its pathology and treatment by antipyretics : being an essay which was awarded the Boylston prize of Harvard University, July, 1890 / by Hobart Amory Hare.

Date:
1891
Catalogue details

Licence: Public Domain Mark

Credit: Fever : its pathology and treatment by antipyretics : being an essay which was awarded the Boylston prize of Harvard University, July, 1890 / by Hobart Amory Hare. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    If the reader will glance at the tables following this page, he will see how the symptoms vary, and how dif- ficult it is to discover more than a few points common to all cases. Notwithstanding this fact, however, it is of some importance to study the results reached by an analysis of the hundred and odd cases here collected. At the very first glance, it is readily seen that the num- ber of instances where untoward effects were present in females is largely in excess of those instances in which they occurred in males; and it is also worthy of note that the prevailing age was decidedly that of full adult life, namely, from 30 to 40 years, both in males and females, as may be seen from the following tables :— Females. Males. Age, 1 to 10 years, 6 cases. Age, 1 to 10 years, 4 cases. 10 to 20 12 10 to 20 5 20 to 30 8 20 to 30 5 « 30 to 40 15 30 to 40 4 « u 40 to 50 2 40 to 50 « 3 50 to 60 2 50 to 60 1 ease. 60 to 70 4 60 to 70 « 1 Passing on, we find that the dose which caused untoward effects was generally a moderate one, and that it was from 10 to 15 grains in most instances, and next most frequently from 5 to 10 grains. It is also to be seen, on analysis, that this proportion holds good in males as well as females, although, of course, to a much less degree. A glance at the next column of the tables, that on the time of onset, will show that this species of information may be divided into two sets. One of these is when the drug was taken for a length of time before bad effects were noted; the other, when the evil effects came from a single or double dose. It will also be seen that, when single or double doses were the cause of the