Serum diagnosis of syphilis and the butyric acid test for syphilis / by Hideyo Noguchi.

Date:
[1911]
Catalogue details

Licence: In copyright

Credit: Serum diagnosis of syphilis and the butyric acid test for syphilis / by Hideyo Noguchi. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    Since the application in 1906 by Wassermann and others of the Bordet-Gengou phenomenon of comple- ment fixation to the diagnosis of syphilis, the large number of publications on the subject, while establish- ing the test as a diagnostic method of real value, have, unfortunately, aided the general medical reader little in gaining a clear conception of the principles in- volved ; and the rapidly growing literature has become too voluminous to enable the average clinical labora- tory worker to obtain exact data on the test, in its various forms. The object of this book is, first, to give a brief yet adequate account of the principles of serum haemol- ysis and of the behaviors of the combinations of anti- gens and antibodies towards hsemolysis, so essential for a proper understanding of the subject, discussing at some length the quantitative relationship of the fac- tors playing a part in these phenomena, an aspect of the subject that has not perhaps received the consid- eration that it deserves; and, secondly, to give in detail the technic of Wassermann's method and of the method recommended by the author. The author has endeavored to treat the subjects of this book in such a manner as to make it suitable for the use of practising physicians and students, and at