The pathological histology of bronchial affections, pneumonia and fibroid pneumonia : an original investigation / by A.G. Auld.

  • Auld, Alexander Gunn.
Date:
1891
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Licence: Public Domain Mark

Credit: The pathological histology of bronchial affections, pneumonia and fibroid pneumonia : an original investigation / by A.G. Auld. Source: Wellcome Collection.

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    cellular cement substance. Further, they possess a small body, which is more opaque than that of the epithelial cell, and containing a small nucleus, which becomes more deeply stained by hsematoxylin than the nucleus of an epithelial cell; and lastly, they are in connection with connective tissue corpuscles in the mucosa—all which, prove them to be inter- epithelial connective tissue cells. He further maintains that these cells and spaces form the only channel of com- munication betwixt the free surface and the mucosa, where- by fluid or formed material can pass either outwards or inwards, notwithstanding that epithelial cells in connection with connective tissue cells have been described by Billroth, Heidenhain, Huxley, and others. Hence Klein would have us believe that the epithelial layer is a compound structure containing a mesoblastic derivative. This theory might indeed appear to receive some support from an experiment of Sikorsky's,* which consisted in introducing a watery solution of carminate of ammonium into the air passages of cats and dogs during life, when it was found that the ordin- ary columnar cells remained unstained, but that peculiar cells —on superficial aspect resembling columnar cells—took up the carmine readily, whence it had penetrated by vertical canals into the lymphatic system of the mucosa. Arnold, f also, by reversing the order of this experiment, found that indigo sulphate of sodium, injected at high pressure into the blood-vessels passed through the lymphatics into the cement substance of the epithelial cells. Now in examining the tracheal epithelium of the rabbit, it will be found that there exist amongst the columnar cells at least three well marked varieties of ovoid cells. First there will be observed (what is especially well marked in the cat) a pyriform cell whose body is a little larger than * Centralblatt f. Med. Wiss., 1870, No. 52. t Virchow's Archiv, vol. 66.