The crystalline lens system : its embryology, anatomy, physiological chemistry, physiology, pathology, diseases, treatment, operations and after-changes ; with a consideration of aphakia / by Louis Stricker.

  • Stricker, Louis, 1863-
Date:
1899
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Licence: Public Domain Mark

Credit: The crystalline lens system : its embryology, anatomy, physiological chemistry, physiology, pathology, diseases, treatment, operations and after-changes ; with a consideration of aphakia / by Louis Stricker. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    nies this, and, like Julie Sinclair,11* he explicitly states that the entrance of pus is always preceded by destruction of the capsule. Since the lens is an epithelial structure, the pus cells must come from without. In cases where there had been an injury to the capsule, their presence was easily explained, but it has been known for a long time that there are cases of spontaneous purulent inflammation in which the presence of the pus cells could not be so easily explained. The question to be decided was, did the cells wander through the capsule by diapedesis, or was the capsule first destroyed as the result of a melting away of the tissue? In his experimental investigations, Deutschman (quoted as above) demonstrated that a local perforation and softening of the capsule did occur, and that entrance to the pus cells was thus given, and he concluded that before this occurred not a single pus cell could enter, though the lens be imbedded in pus. Both Leber 12 and Wagenman 13 corroborated these investigations. Leber states: Aside from the larger holes, numerous microscopical perforations are observed, in which solitary or groups of cell? are found, and between these cocci. Wagenman suggested that it ap- peared as though the cocci first entered the capsule, and that the pus cells then followed. Otherwise, he states, it would be difficult to explain why these perforations should occur in circumscribed areas, rather than attack the entire surface of the capsule to an equal degree. Thus there still re- mained to be explained, what it is that produces this softening and melt- ing down of the capsule. This Leber has done in his exhaustive, critical and experimental work, Die Entstehung der Entzundung und der Wirkung der Entzundung erregenden Schadlichkeiten, Leipsig, 1891; and he has made it the subject of special observation and criticism in the 38th chapter, Purulent softening and 'melting down' of tissues. He states (p. 528) that a purulent exudate free of microbes contains an enzym which has a fluidifying effect on fibrin, gellatin and dead animal tissue; that this enzym is produced by the leucocytes, but acts independently of them on surrounding tissues. In purulent inflammations this enzym is the prin- cipal factor in dissolving fibrin and animal tissues, and also in preventing the coagulation of fibrin. The prevention of coagulation is clue to the fact that the fibrinogen in the exudate or the already coagulated fibrin is con- verted into a non-coaguble pepton-like substance by the action of the na Experimented Ilntersuchungen ur Genese der Erworbenen Kapsel Cat- aract. Inaug. Dissert, 1870. l^Bericht uber die XX Ver*. d'Opth. Gessel, 1889. Zehenders M., B. 1, XXVII. Beilagh Heft.. 8-45. 13 Uber die von Operatlonsnarben und Vernarbten Iris voi'fallen nugehende Glaskorpcr eiterung. Von Gni.-f Arch.. XXXV. 4, S. 140-144. 1889.