The pituitary body and its disorders : clinical states produced by disorders of the hypophysis cerebri. An amplification of the Harvey Lecture for 1910.

  • Cushing, Harvey, 1869-1939.
Date:
1912
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Licence: In copyright

Credit: The pituitary body and its disorders : clinical states produced by disorders of the hypophysis cerebri. An amplification of the Harvey Lecture for 1910. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    (b) Distant lesions with hypopituitarism Case XL: Congenital hydrocephalus with adiposity and hypophyseal defor- mation. Operation. Autopsy 204 Case XLI: Cystic cerebellar glioma with hydrocephalus and hypophyseal deformation. Operation. Autopsy 2()() CaseXLII: Cerebral endothehoma with ventricular hydrops and hypopit- uitarism. Operation. Autopsy 208 Group V.—Cases showing a polyglandular syndrome. Discussion of term 211 Case XLIII: Pluriglandular insufficiency of hypophysis, thyroid, adrenal and ovary. Pituitary feeding 213 Case XLIV: Pluriglandular syndrome, suggesting pituitary, adrenal, testis, thymus and thyroid 215 Case XLV: Pluriglandular syndrome, suggesting pituitary, adrenal, pineal or ovary. Decompression operation. T>\s,Q,\is^\on oi hyperadrenalism 217 Case XLVI: Infantilism with hypertrichosis, pigmentation, amenorrhoea and uncinate fits. Infundibular exploration 221 CaseXLVII: Sexual precocity; gigantism; adiposity, with hydrocephalus. Discussion of pinealism and the role of the interstitial cells of Leydig 224 PART III INCIDENCE, SYMPTOMATOLOGY AND TREATMENT. Incidence. Inheritance. Traumatism. Physiological epochs (adolescence, hiber- nation, pregnancy). Acute infectious maladies. Vascular disease 231 Neighborhood Symptoms. Subjective discomforts. Deformation of the sella tur- cica: varieties. Radiographic interpretations. Visual disturbances; optic atrophy ; exophthalmos ; perimetric deviations; pupillary changes ; oculomotor disturbances. Uncinate symptoms. Nasopharyngeal signs : epistaxis; rhinor- rhoea 237 General Pressure Symptoms 248 Glandular Manifestations. Modifications of skeletal development; overgrowth. Theories of acromegaly and gigantism. Glandular instability. Skeletal under- growth. Discussion of infantilism, chetivism, ateliosis. Cutaneous and sub- cutaneous changes in hyperpituitarism and hypopituitarism. Adiposity: child- hood types; adolescent types; adult types. Carbohydrate tolerance and hypophy- seal diabetes. Polyuria and diabetes insipidus. Thermic changes. Blood pres- sure. Somnolence. Mental symptoms and epilepsy 248 Symptoms Referable to Other Ductless Glands. The sexual organs, thyroid, parathyroids, adrenals, thymus, pancreas, and pineal glands 275 Pathology of Glandular Lesions. Physiological and pathological hyperplasia. Hypophyseal tumors proper. Glandular strumas. Extrapituitary tumors 284 Treatment. Surgical indications: (1) for the rehef of general pressure symptoms; (2) to combat functional hyperplasia; (3) for the relief of neighborhood symp- toms. Operative methods: intracranial versus transphenoidal. Author's pro- cedure. Operative results: tabulation of 43 cases 291 Medicinal Measures. Glandular administration. Radiotherapy 315 Bibliography 323 Index 335