The pituitary body and its disorders : clinical states produced by disorders of the hypophysis cerebri. An amplification of the Harvey Lecture for 1910.

  • Cushing, Harvey, 1869-1939.
Date:
1912
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Licence: In copyright

Credit: The pituitary body and its disorders : clinical states produced by disorders of the hypophysis cerebri. An amplification of the Harvey Lecture for 1910. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    pressure disturbances on the part of the encephalon, and wiH be reawakened m view of the possible relation of epilepsy to glandular insufficiency The gj-nascological and genito-urinary clinics have long lieen frequented bv the fat amenorrhoeics and impotent males with hj-pophyseal disease; and the studies of Erdheim and Stumme will give the scientific obstetrician reason for hypophyseal study for years to come. The experimental and morbid anatomist has been aroused to renewed interest in the ductless glands par- ticularly from the standpoint of their interrelational activity. The imoort ance of forcing a knowledge of these states upon the internist, and especially upon the pediatrician, is evident when we realize that except for the adult acromegalic conditions the manifestations of hypophyseal disease have been afrls nf1^ overlooked, and now that organotherapy promises much for all cases of glandular insufficiency whether adult or infantile it will need no prodding to bring this about. Specialists whose activities are as divergent as are those of the actmographer and the physiological chemist are now called upon, not only to aid in matters of diagnosis, but it lies in their province to add materially to our further knowledge of the subject. To the general sur- dntL s*'M Tl'^^ 'l^'^^ ' ^^^^ ^^^^ unanticipated- duties similar to those he has assumed in the case of such thyroid enlargements as are productive of pressure disturbances. And needless to say to the operating specialist in maladies of the nose and throat the subject is of prime importance, not only because the hypophysis itself abuts upon his preserves SossfhTv b?^'''^ -'T '^f r''' ^ pharyngeal organ which ma^ possibly be a not infrequent seat of disea.se and which may possess some physiological properties of importance to the organism In presenting the original lecture at the invitation of the Harvey ■Society under my own name, I felt that I was acting merely as the spokes- man for my several assistants and co-workers in the Johns Hopkins Hospital cluTwT ^^^^'^^P'' especially Drs. S. J. Crowe, John Homans, Emil Goetsch Walter E. Dandy and Conrad Jacobson. Such investigations a have been undei-teken require the mutual industry of a group of workers The task IS not for an individual, and without cooperative devotion to the prob- lems concerned It would have been impossible to have made even our little progress toward a better understanding of the function of the hypophysis m health and disease. Jfij^ I wish to express my deep obligation to Professor Halsted, in whose Surgical Service at the Johns Hopkins Hospital the clinical studies have been made, to Professor Welch and his associates of the Pathological Department tor their generosity in giving my assistants and myself the privilege of mak- ing our own first-hand studies of the fatal cases; to Dr. F. H Baetier the Aotinographer of the hospital, and his assistants, Dr. Boardman and Dr. Waters, for their cordial collaboration. I am indebted to Mr. Louis S Brown of the Massachusetts General Hospital for a number of the microphoto- f^-sh'lT ^r^Ti'^u^ ^° ^^^y Srinkley, my secretary, 1 wish likewise to add here my acknowledgment of gratitude. Baltimore, September 15, 1911.