The skin manifestations associated with leukaemia and allied conditions / Sir Humphry Rolleston, Bt., K.C.B., M.D., D. Sc., P.R.C.P.

  • Rolleston, Humphry Davy, Sir, 1862-1944.
Date:
[1924?]
Catalogue details

Licence: In copyright

Credit: The skin manifestations associated with leukaemia and allied conditions / Sir Humphry Rolleston, Bt., K.C.B., M.D., D. Sc., P.R.C.P. Source: Wellcome Collection.

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    WITH THE AUTHOR'S COMPLIMENTS. cP \ \cPjS V ✓ xV /? ^ n THE SKIN MANIFESTATIONS ASSOCIATED WITH LEUKAEMIA AND ALLIED CONDITIONS.*! Sir HUMPHRY ROLLESTON, Bt., K.C.B., M.D., D.Sc., P.R.C.P. Introduction. A discussion of this kind is of special value, as it deals with a subject on the borderland between general medicine and dermatology, and thus tends to bring together for their mutual benefit those whose devotion to their own line of work might otherwise isolate. In the first place it is advisable to mention the conditions allied to leukaemia that come within the scope of this discussion. Some of the conditions described as causing cutaneous manifestations may be neglected because they are probably more accurately included under other headings. As lymphodermia perni- ciosa was described by Kaposi in 1885, before differential blood-counts were in vogue, it cannot now be regarded as a distinct condition or decided whether it was leukaemia, or, as some consider, mycosis fun- goides. It is therefore desirable that the term “lymphodermia perni- ciosa” should be allowed to lapse. “Pseudo-leukaemia, a term responsible for much confusion, will be omitted, as it is probably covered by the aleukaemic phase of leukaemia or by Hodgkin’s disease. C. Sternberg’s leukosarcoma is characterized by a tumour, in the vast majority of cases in the mediastinum, glandular enlargement, infiltration of the viscera, and eventually by the escape into the blood of the tumour- cells, which are usually large lymphocytes, 5-6 u in diameter. Chloroma, though considered as distinct from, evidently is allied to * Read at the Fourth Annual Meeting of the British Association of Dtimato logy and Syphilology, July, 1924. t Reprinted from the British Journal of Dermatology and Syphilis, 19-4, Yol. XXXYI, pp. 407-427. /