The leprous diseases of the eye / by O.B. Bull and G.A. Hanson.

  • Bull, O. B. (Ole Bornemann), 1842-1916.
Date:
1873
Catalogue details

Licence: Public Domain Mark

Credit: The leprous diseases of the eye / by O.B. Bull and G.A. Hanson. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    may be overcast with vessels extending far over the Cornea. When the Hypersemia has existed for some time, it goes back again, but leaves a greater obscuration. The more frequently the vascular injection occurs, the less completely it usually dis- appears; and in a more advanced stage, we have always found the obscuration also macroscopicallv covered with vessels. As the process advances, more and more of the Cornea becomes obscured; but it is an exceptional case when the whole Cornea is darkened in this manner. The centre usually remains free; but we have seen cases in which the whole surface of the Cornea had become opaque, and had the appearance of dull ground glass. For microscopic examination we have procured some quite fresh preparations of the superficial corneal affection with the distinct spot-like obscurations, by cutting with a cataract-knife small superficial slices from the Cornea, and examined them in V2 °/0 solution of chloride of soda. No permanent obscuration remained after this operation. While in a successful preparation, no distinctly formed ele- ments are discovered in those places where no obscuration occurs, such elements may be noticed under the normal epithelium which gradually becomes more and more distinctly perceptible — keeping the lower limits of the epithelium still well defined — in those places where the spot-like obscurations can macroscopically, or with the aid of a magnifying glass, be observed. The elements which are here found together in groups are mostly quite small, of the size a white blood-globule and .even less. In one case all the elements were slightly opaque; in another case the larger of them, of which some attained a con- siderable size, were finely granulated; and some had a slight brownish tint. In one preparation obtained some hours after death, all the elements had a strong yellow brown color (Fig. 3. Hartnack 7—3). This difference in color is evidently the expression of various age in the elements of the spots. The brown color, and the fine granulation always indicate the regres- sive metamorphosis of the elements in leprous products, when this metamorphosis takes place sufficiently slowly (G. A. Hansen Nord. med Archiv B. 1 No. 13 forelobige Bidrag til Lepraens Characteristik og B. 11 No. 16 fortsatte Bidrag). Where the obscuration is even, blood-vessels always appear